内科的治療で改善しその前後で,血清並びに,胃粘膜内ペプシノーゲンの推移を観察し得たメネトリエ病の1例

• 小島 真二

  至誠会第二病院消化器内科

• 足立 ヒトミ

• 新浪 千加子

• 古川 みどり

• 鈴木 義之

• 根本 行仁

  東京女子医科大学消化器内科

• 池田 みどり

• 黒川 きみえ

• 河上 牧夫

  東京女子医科大学病院病理科

書誌事項

タイトル別名

• A CASE REPORT OF MENETRIER'S DISEASE WITH IMPROVEMENT BY MEDICATION, IN WHICH CHANGES OF PEPSINOGEN IN SERUM AND GASTRIC MUCOSA WERE MEASURED BEFORE AND AFTER TREATMENT

抄録

The case Wasa 49-years-old male who visited our hospital complaining of decreased body weight and anorexia. Laboratory data on admission showed hypoalbuminemia and gastroendoscopy revealed hypertrophic mucasa in the gastricbody. Gastric juice analysis revealed hypoacidity and protein losing. This case was diagnosed as Menetrier's disease. Improvement was obtained by the treatment with famotidine and enteral tube elemental diet therapy. Serum pepsinogen (abbreviated as PG hereinafter) of the patient was determined before and after the treatment. Before the treatment, serum PG- and PG-II were both at abnormally high values, but the numbtrof cells containing PG granules decreased in the gastric mucosa. The difference between serum and gastric mucosa in PG-cotent was revealed. After the treatment, serum PG levels and distribution of PG granules in the gastric mucosa became normalized. This case was interesting from the point of view of elucidating the mechanism of transmigration of PG to the blood.

収録刊行物

• 日本消化器内視鏡学会雑誌

  日本消化器内視鏡学会雑誌 37 (3), 600-606_1, 1995

  一般社団法人 日本消化器内視鏡学会

詳細情報

• CRID: 1390001204217525760
• NII論文ID: 130004253798
• NII論文ID: 10006812809
• NII書誌ID: AN00192102
• DOI: 10.11280/gee1973b.37.600
• ISSN: 18845738
• ISSN: 03871207
• Web Site: https://search.jamas.or.jp/link/ui/1995185483
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可