Evaluation of Recurrence in 36 Subacute Thyroiditis Patients Managed with Prednisolone.
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- MIZUKOSHI Tsunenori
- the Noguchi Thyroid Clinic and Hospital Foundation
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- NOGUCHI Shiro
- the Noguchi Thyroid Clinic and Hospital Foundation
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- MURAKAMI Tsukasa
- the Noguchi Thyroid Clinic and Hospital Foundation
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- FUTATA Tetsuhiro
- the Noguchi Thyroid Clinic and Hospital Foundation
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- YAMASHITA Hiroyuki
- the Noguchi Thyroid Clinic and Hospital Foundation
この論文をさがす
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Objective The incidence of subacute thyroiditis (SAT) is low and there are a few reports of recurrence of subacute thyroiditis. Current treatment protocols for SAT are not uniform. Prednisolone (PSL) is chosen more often for treatment than nonsteroidal anti-inflammatory drugs. This study was undertaken to confirm the recurrence rate of SAT managed by PSL, and to compare the initial laboratory data between the recurrent and the non-recurrent groups.<br> Methods After diagnosis, all patients were treated with PSL (starting at 30 mg or 25 mg per day, tapered by 5 mg per week) for 5 or 6 weeks. We evaluated data and symptoms at the first visit and during the therapy.<br> Patients Thirty-six patients who received only PSL for SAT at our hospital between January 1997 and December 1998 were referred. These patients asked to visit every 2 weeks for the monitoring of symptoms and laboratory data.<br> Results SAT symptoms recurred in eight patients (22 %), most upon cessation of PSL. There was no difference in initial serum sialic acid, erythrocyte sedimentation rate, C-reactive protein, thyroglobulin, serum free thyroxine and free triiodothyronine before PSL treatment between the recurrent and non-recurrent patient populations.<br> Conclusions The recurrence rate of SAT with treated PSL is about 20%. There was no difference in the laboratory data before starting the therapy between recurrent and non-recurrent groups. Therefore, a modified protocol of PSL administration may be needed to decrease the early recurrent rate of SAT.<br>(Internal Medicine 40: 292-295, 2001)
収録刊行物
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- Internal Medicine
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Internal Medicine 40 (4), 292-295, 2001
一般社団法人 日本内科学会
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詳細情報
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- CRID
- 1390001204867663488
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- NII論文ID
- 10006999523
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- NII書誌ID
- AA10827774
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- COI
- 1:CAS:528:DC%2BD3MXltV2ku7w%3D
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- ISSN
- 13497235
- 09182918
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- NDL書誌ID
- 5757976
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- PubMed
- 11334386
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 使用不可