Crow-Fukase Syndrome with Ischemic Cardiomyopathy.

  • ICHIKAWA Yoshihiko
    the Second Department (Cardiology) of Internal Medicine, Sapporo Medical University School of Medicine
  • NAKATA Tomoaki
    the Second Department (Cardiology) of Internal Medicine, Sapporo Medical University School of Medicine
  • OHHATA Junichi
    the Second Department (Cardiology) of Internal Medicine, Sapporo Medical University School of Medicine
  • WAKABAYASHI Takeru
    the Second Department (Cardiology) of Internal Medicine, Sapporo Medical University School of Medicine
  • SASAO Hisataka
    the Second Department (Cardiology) of Internal Medicine, Sapporo Medical University School of Medicine
  • TSUCHIHASHI Kazufumi
    the Second Department (Cardiology) of Internal Medicine, Sapporo Medical University School of Medicine
  • SHIMAMOTO Kazuaki
    the Second Department (Cardiology) of Internal Medicine, Sapporo Medical University School of Medicine
  • CHIBA Susumu
    Department of Neurology, Sapporo Medical University School of Medicine
  • MATSUMOTO Hiroyuki
    Department of Neurology, Sapporo Medical University School of Medicine

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A 31-year-old man was admitted to our hospital for further evaluation of heart failure symptoms. Crow-Fukase syndrome was diagnosed on the basis of findings of polyneuropathy, hepatomegaly, monoclonal hypergammaglobulinemia, and hypertrichosis. Dipyridamole-stress thallium-201 perfusion imaging, contrast left ventriculography, and coronary angiography revealed a markedly dilated and dysfunctioning left ventricle, extensive reversible ischemia with fixed defect, and multiple coronary lesions. Histopathology of myocardial biopsy specimens demonstrated ischemia-induced myocardial necrosis. These findings suggested that ischemic cardiomyopathy, probably due to inflammatory reactions of coronary arteries in Crow-Fukase syndrome, was responsible for the heart failure symptoms and left ventricular dysfunction in this patient.<br>(Internal Medicine 40: 726-730, 2001)

収録刊行物

  • Internal Medicine

    Internal Medicine 40 (8), 726-730, 2001

    一般社団法人 日本内科学会

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