Thyrotropin Secreting Pituitary Adenoma Effectively Treated with Octreotide.

  • FUKUDA Taku
    The First Department of Internal Medicine, Nagasaki University School of Medicine
  • YOKOYAMA Naokata
    The First Department of Internal Medicine, Nagasaki University School of Medicine
  • TAMAI Mami
    The First Department of Internal Medicine, Nagasaki University School of Medicine
  • IMAIZUMI Misa
    The First Department of Internal Medicine, Nagasaki University School of Medicine
  • KIMURA Hironori
    The First Department of Internal Medicine, Nagasaki University School of Medicine
  • TOMINAGA Tan
    The First Department of Internal Medicine, Nagasaki University School of Medicine
  • ASHIZAWA Kiyoto
    The First Department of Internal Medicine, Nagasaki University School of Medicine
  • KIRIYAMA Takeshi
    The First Department of Internal Medicine, Nagasaki University School of Medicine
  • YOSHIMINE Hiroyuki
    The Department of Internal Medicine, Institute of Tropical Medicine, Nagasaki University
  • OHISHI Kazunori
    The Department of Internal Medicine, Institute of Tropical Medicine, Nagasaki University
  • EGUCHI Katsumi
    The First Department of Internal Medicine, Nagasaki University School of Medicine

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抄録

We report a 65-year-old woman with thyrotropin (TSH) secreting pituitary adenoma, who was diagnosed based on the lack of inhibition of serum TSH despite an increased serum free thyroxine (T4), a low response of serum TSH to thyrotropin releasing hormone, and a pituitary tumor as revealed by magnetic resonance imaging. The pituitary adenoma was, however, inoperable due to chronic respiratory failure. The treatment with octreotide in a dose of 100 μg b.i.d. resulted in inhibition of serum TSH and free T4 to euthyroid levels and considerable shrinkage of the pituitary tumor. These effects were continued over 8 months after the start of octreotide therapy without any adverse effects. These findings add further evidence that octreotide is useful for treating inoperable TSH secreting pituitary adenoma.<br>(Internal Medicine 37: 1027-1030, 1998)

収録刊行物

  • Internal Medicine

    Internal Medicine 37 (12), 1027-1030, 1998

    一般社団法人 日本内科学会

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