糖尿病性神経障害患者におけるＳｅｍｍｅｓ‐Ｗｅｉｎｓｔｅｉｎ　Ｍｏｎｏｆｉｌａｍｅｎｔｓ法の有用性

• 神 康之

  北里大学医学部内科

• 金森 晃

  北里大学医学部内科

• 藤田 芳邦

  北里大学医学部内科

書誌事項

タイトル別名

• Use of Semmes-Weinstein Monofilaments for Evaluating the Severity of Diabetic Neuropathy.
• トウニョウビョウセイ シンケイ ショウガイ カンジャ ニ オケル Semmes-Weinstein Monofilamentsホウ ノ ユウヨウセイ

抄録

We assessed the reliability of Semmes-Weinstein monofilaments for evaluating diabetic neuropathy in 150 patients with type 2 diabetes and 52 healthy subjects. The touch perception threshold (TPT) was measured at the plantar surface of thegreat toe using 3 sizes of monofilaments-4.17, 5.07, and 6.10 bending with 1, 10 and 100g of force.<BR>The TPT did not exceed 4.17 (1g) in 98%(51) of healthy subjects.<BR>The TPT of 11 of the type 2 diabetics wasgrade 6.10 (100g), of 52grade 5.07 (10g), and of 87grade 4.17 (1g). TPTgrades were strongly associated with other neurological functions, such as Achilles tendon reflex, vibration perception threshold, nerve conduction study, current perception threshold, and postural fall in blood pressure. Atgrade 4.17 (1g), patients showed only slight abnormalities in other neurological tests and none had foot ulceration. Atgrade 5.07 (10g), almost all patients had abnormalities in other neurological tests. At grade 6.10 (100g) all patient had severe neuropathy and 90.9% had a history of foot ulceration.<BR>We thus conclude that TPT measurement by Semmes-Weinstein monofilaments is useful for evaluating the severity of diabetic neuropathy.

収録刊行物

• 糖尿病

  糖尿病 44 (3), 209-216, 2001

  一般社団法人 日本糖尿病学会

キーワード

• 糖尿病性神経障害
• 触覚閾値
• 糖尿病足病変
• 神経伝導検査

詳細情報

• CRID: 1390001204905435008
• NII論文ID: 130004338752
• NII論文ID: 10007045054
• NII書誌ID: AN00166576
• DOI: 10.11213/tonyobyo1958.44.209
• ISSN: 1881588X
• ISSN: 0021437X
• NDL書誌ID: 025094918
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I025094918
• Web Site: https://search.jamas.or.jp/link/ui/2003014970
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可