肝門部胆管癌の肝臓側胆管における進展様式の検討

DOI 被引用文献10件 参考文献10件

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  • Histopathological analysis on the mode of tumor extension to the intrahepatic bile duct of hilar bile duct cancer

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The mode of cancer cell extension along the intrahepatic bile duct was studied histopathologically in serial sections of surgical specimens taken from 53 patients with hilar bile duct cancer. Two modes of extension were observed, a mucosal type (M: n=18) and an adventitial type (A: n=35). In the M type, cancer cells prominently infiltrated the mucosal layer rather than the adventitia. In contrast, A type cancer cells extend conspicuously along the adventitia. As to the macroscopic or histological characteristics of the lesions showing M type tumor extension,88% of them were grossly papillary type and papillary adenocarcinoma accounted for 12 out of 16 lesions (75%). On the other hand, A type tumor extension was more common in the cases with grossly infiltrating type and tubular adenocarcinoma including 5 cases with poorly differentiated type. In the cases with tumor with A type extension pattern, positive rate of residual cancer at the resection margin was significantly higher than that of M type.

収録刊行物

  • Tando

    Tando 10 (2), 131-137, 1996

    Japan Biliary Association

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