呼吸器・尿路感染症におけるNM441の臨床的検討

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  • Clinical studies of NM441 in respiratory infections and urinary tract infections

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We carried out clinical studies on NM441.<BR>NM441 was administered to 19 patients with respiratory infections and urinary tract infections at 100mg once daily or 100-200mg b. i. d. for 3 to 10 days.<BR>Nineteen patients, 2 with upper respiratory tract infections, 7 with acute bronchitis, 4 with pneumonia, 4 with secondary infections of chronic respiratory diseases and 2 with urinary tract infections, were studied in a clinical evaluation of NM441. Clinical efficacy rate was 89.5%.<BR>Of 17 strains (9 spiecies) isolated from 15 patients before treatment, 16 were eradicated after treatment, but one was replaced.<BR>No side effects were observed. With regard to abnormal laboratory findings, eosinocytosis, elevated serum creatinine and decreased WBC were noted in each one case.

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