書誌事項
- タイトル別名
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- Clinical study on NM441 against respiratory tract infection
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NM441 was orally administered to 15 patients with acute or chronic respiratory infections (2 cases with acute bronchitis, 9 with pneumonia, 2 with chronic bronchitis, 1 with middle lobe syndrome with infection and 1 with old pulmonary tuberculosis with infection) at a dose of 100 or 200mg twice a day, and its clinical efficacy, bacteriological efficacy, side effects and abnormal laboratory findings were investigated.<BR>The clinical efficacy was excellent in 4 cases, good in 9, poor in 1 and unknown in 1, with the efficacy rate of 92.9%.<BR>In the bacteriological efficacy, a total of 4 strains, 3 strains of Haemophilus influenzae and 1 of Burkholderia cepacia were isolated from 4 patients. All of H. influenzae were eradicated and B. cepacia was decreased.<BR>Though nausea·vomiting was observed in 1 patient as a side effect and an elevation of BUN·Coombs' test positive was observed in 1 as an abnormal laboratory finding, both of them were not particularly problematic.<BR>From the above results, NM441 was considered as a useful drug for the treatment of mild or moderate respiratory tract infections.
収録刊行物
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- 日本化学療法学会雑誌
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日本化学療法学会雑誌 44 (Supplement1), 626-629, 1996
公益社団法人 日本化学療法学会
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詳細情報 詳細情報について
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- CRID
- 1390001206289261440
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- NII論文ID
- 10007601955
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- NII書誌ID
- AN10472127
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- ISSN
- 18845886
- 13407007
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
