胆道系におけるアンスロン‐ＰＵカテーテルの細菌接着抑制効果

• 長岡 昭二

  東京都立大学工学部工業化学科

• 川上 浩良

  東京都立大学工学部工業化学科

• 本間 久登

  札幌医科大学第四内科

書誌事項

タイトル別名

• Reduction of Bacterial Adherence to Heparinized Hydrophilic Catheter(Anthron-PU) in Percutaneous Biliary Drainage.

抄録

We have previously reported the inhibitory effect of heparinized hydrophilic polymer (Anthron^TM) on in vitro bacterial adhesion and biofilm formation. In the present study, we employed polyurethane catheters coated with Anthron for the patients with malignant obstructive jaundice to perform percutaneous biliary drainage for a long period Following implantation into the bile duct, catheters were withdrawn to check for bacterial adhesion to the lumen by scanning electron microscopy and bacterial culture. In bacterial cultures of withdrawn catheters, only Enterncoccus faecium was identified While in the lumens of silicone catheters used as controls, severe biofilm formations were found, in which 6 strains gram-negative and 2 strains gram-positive bacteria were identified These results suggest that the clinical use of the catheters coated with Anthron in the biliary system is considered to be effective in preventing catheter-related obstruction and infections.

収録刊行物

• 人工臓器

  人工臓器 25 (2), 412-416, 1996

  一般社団法人 日本人工臓器学会

キーワード

• Heparinized hyd rophilic polymer (Anthron)
• Obstructive jaundice
• End oprosthesis
• Implantable port
• Biofilm formation

詳細情報

• CRID: 1390001204956574080
• NII論文ID: 10007718103
• NII書誌ID: AN00120167
• DOI: 10.11392/jsao1972.25.412
• ISSN: 18836097
• ISSN: 03000818
• Web Site: https://search.jamas.or.jp/link/ui/1996230315
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可