Isolation and Synthesis of Cosmetic Substances from African Dietary Leaves, Celosia argentea L. for Skin Depigmentation

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Six compounds were isolated from the leaves of Celosia argentea L.. Tyrosinase inhibitory and superoxide scavenging activity of the compounds was examined so as to obtain a skin depigmentation agent for cosmetic application. Eugenyl O-β-D-glucopyranoside (citrusin C, 1) showed strong tyrosinase inhibitory activity. Two-step inhibitory effects of successive tyrosine and DOPA oxidation for tyrosinase were stronger compared to arbutin used commercially at present (47.20% inhibition of tyrosine oxidation and 87.93%, DOPA oxidation, compared to 63.00% for tyrosine and 7.70% for DOPA oxidation in the case of arbutin). Moreover, we succeed in providing compound 1 abundantly in the synthetic study which used acetobromo-α-D-glucose and Sn(OTf)<SUB>2</SUB>.

収録刊行物

  • Journal of oleo science

    Journal of oleo science 51(3), 203-206, 2002-03-01

    公益社団法人 日本油化学会

参考文献:  11件中 1-11件 を表示

被引用文献:  1件中 1-1件 を表示

各種コード

  • NII論文ID(NAID)
    10008009780
  • NII書誌ID(NCID)
    AA11503337
  • 本文言語コード
    ENG
  • 資料種別
    NOT
  • ISSN
    13458957
  • NDL 記事登録ID
    6066841
  • NDL 雑誌分類
    ZP25(科学技術--化学・化学工業--油脂類)
  • NDL 請求記号
    Z54-J571
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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