タンパク質介在の細胞膜ガス輸送  [in Japanese] Gas Transport Mediated by Proteins in Cell Membranes  [in Japanese]

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Author(s)

    • 藤瀬 浩 FUJISE Hiroshi
    • 麻布大学獣医学部病態生化学研究室 Laboratory of Pathobiochemistry, School of Veterinary Medicine, Azabu University

Abstract

Transports of water and gases through cell membranes have conventionally been considered to diffuse across the lipid bilayer. Recently, however, it was reported that water transport was mediated by water channel, aquaporin (AQP). Gas permeation, such as CO<SUB>2</SUB> and NH<SUB>3</SUB>, was greatly restricted by the apical membrane in epithelia of the urinary tract or colon crypt, a restriction not explained by diffusion. The reason for this low permeation rate was considered to be the difference in lipid composition of the cell membranes. On the other hand, band 3 and AQP have been suggested as possible gas or CO<SUB>2</SUB> channels. In 1998, several reports indicated that AQP1 enhanced CO<SUB>2</SUB> permeation of cell membranes or might be the CO<SUB>2</SUB> channel, although other study disagreed. Recent studies on gas permeation of the cell membrane mediated by protein or an as yet unspecified channel were reviewed.

Journal

  • MEMBRANE

    MEMBRANE 26(2), 66-71, 2001-03-01

    THE MEMBRANE SOCIETY OF JAPAN

References:  20

Cited by:  1

Codes

  • NII Article ID (NAID)
    10008010309
  • NII NACSIS-CAT ID (NCID)
    AN0023215X
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    03851036
  • NDL Article ID
    5724190
  • NDL Source Classification
    ZR2(科学技術--生物学--生化学)
  • NDL Call No.
    Z18-1127
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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