生体膜とガス Biomembranes and Gases

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Besides O<SUB>2</SUB> and CO<SUB>2</SUB>, many small molecules can be transferred between respiratory gases and blood. There is an alveocapillary membrane between respiratory gases and blood, that consists of alveolar epithelium and capillary endothelium, and gases should transfer via these cell membranes. Artificial lungs consist of polypropylene membranes, of which the thickness is nearly the same as that of the thin portion of the alveocapillary membrane in natural lungs (-0.5μm).<BR>Volatile anesthetics are administered with inspired gas, and anesthetic molecules transter and interact with biomembranes to cause anesthesia. Both the interactions between anesthetics and functional proteins and those between anesthetics and membrane lipids are important to induce anesthesia. Membrane lipids are not simply the supporting matrix of the functional proteins, they also sometimes control the function of proteins.<BR>In patients poisoned with volatile compounds, some of the compounds are usually eliminated in the expired gas. Since the method of obtaining expired gas is the least invasive, it may be the most practical sample to monitor cases of poisoning.<BR>The gas transfer at alveolar provides much useful information about the body condition.

収録刊行物

  • 膜 26(2), 72-78, 2001-03-01

    日本膜学会

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各種コード

  • NII論文ID(NAID)
    10008010330
  • NII書誌ID(NCID)
    AN0023215X
  • 本文言語コード
    JPN
  • 資料種別
    REV
  • ISSN
    03851036
  • NDL 記事登録ID
    5724192
  • NDL 雑誌分類
    ZR2(科学技術--生物学--生化学)
  • NDL 請求記号
    Z18-1127
  • データ提供元
    CJP書誌  NDL  J-STAGE 
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