Nutritional Effects of Cyclodextrins on Liver and Serum Lipids and Cecal Organic Acids in Rats

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Author(s)

Abstract

The effect of dietary cyclodextrins on liver and serum lipids and cecal organic acid production was investigated. Male Wistar rats were fed a.basal diet and a diet contain-ing 5% of α-, β-, or γ-cyclodextrin. The body weight gain in rats fed the α-cyclodextrin diet was not significantly different from rats fed the other three kinds of diets. The feeding of di-etary α-cyclodextrin increased total lipid and phospholipids in the liver. β-Cyclodextrin sig-nificantly lowered serum total cholesterol and phospholipid levels compared with the basaldiet et al. A decrease in serum triacylglycerol levels was also observed in β-cyclodextrin-fed rats. Dietary α-cyclodextrin significantly increased the weight of cecal tissues and contents, and an approximate fourfold increase in acetate, propionate, and total organic acids was noted, indicating the fermentibility of β-cyclodextrin compared with the basal diet. It seems likely that the suppression of serum cholesterol levels by α- and, 3-cyclodextrins might be due to the increasing acetate and propionate productions in the cecum.

Journal

  • Journal of Nutritional Science and Vitaminology

    Journal of Nutritional Science and Vitaminology 47(5), 335-339, 2001-10-01

    Center for Academic Publications Japan

References:  21

Codes

  • NII Article ID (NAID)
    10008015658
  • NII NACSIS-CAT ID (NCID)
    AA00703822
  • Text Lang
    ENG
  • Article Type
    ART
  • ISSN
    03014800
  • NDL Article ID
    5988753
  • NDL Source Classification
    ZR2(科学技術--生物学--生化学)
  • NDL Call No.
    Z53-B484
  • Data Source
    CJP  NDL  J-STAGE 
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