Serum Cholesterol-lowering Effect of Fermented Milk with Streptococcus thermophilus TMC 1543

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Author(s)

Abstract

The serum cholesterol lowering action of fermented milk with Streptococcus thermophilus TMC 1543 (1543FM), the mechanism behind the cholesterol lowering activity and the active factor in animal experiments were investigated using rats. The serum total cholesterol level of the group fed 1543FM was significantly lower than that of the control group (P<0.05). However, there were no serum cholesterol lowering activities in fermented milks with the other two lactic acid bacteria. The serum total cholesterol concentration of the group fed low-molecular-weight fraction (LMF) from 1543 FM was significantly lower than that of the control group (P<0.05). High-molecular-weight fraction (HMF) also tended to lower serum cholesterol level in the present animal study. The amounts of excretion of both total bile acid and neutral sterol in feces of the 1543FM group increased significantly in comparison with the control group (P<0.05). These results suggest that the mechanism behind serum cholesterol lowering activity of 1543FM would be attributable to the promotion of excretion of bile acid and neutral steroid through feces, and probably the low-molecular material in LMF.

Journal

  • Nihon Chikusan Gakkaiho

    Nihon Chikusan Gakkaiho 72(1), 54-62, 2001-01-01

    Japanese Society of Animal Science

References:  30

Cited by:  1

Codes

  • NII Article ID (NAID)
    10008020599
  • NII NACSIS-CAT ID (NCID)
    AN00195188
  • Text Lang
    ENG
  • Article Type
    Journal Article
  • ISSN
    13443941
  • NDL Article ID
    5646874
  • NDL Source Classification
    ZR22(科学技術--農林水産--畜産)
  • NDL Call No.
    Z18-348
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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