Serum Cholesterol-lowering Effect of Fermented Milk with Streptococcus thermophilus TMC 1543

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The serum cholesterol lowering action of fermented milk with Streptococcus thermophilus TMC 1543 (1543FM), the mechanism behind the cholesterol lowering activity and the active factor in animal experiments were investigated using rats. The serum total cholesterol level of the group fed 1543FM was significantly lower than that of the control group (P<0.05). However, there were no serum cholesterol lowering activities in fermented milks with the other two lactic acid bacteria. The serum total cholesterol concentration of the group fed low-molecular-weight fraction (LMF) from 1543 FM was significantly lower than that of the control group (P<0.05). High-molecular-weight fraction (HMF) also tended to lower serum cholesterol level in the present animal study. The amounts of excretion of both total bile acid and neutral sterol in feces of the 1543FM group increased significantly in comparison with the control group (P<0.05). These results suggest that the mechanism behind serum cholesterol lowering activity of 1543FM would be attributable to the promotion of excretion of bile acid and neutral steroid through feces, and probably the low-molecular material in LMF.

収録刊行物

  • 日本畜産學會報 = The Japanese journal of zootechnical science

    日本畜産學會報 = The Japanese journal of zootechnical science 72(1), 54-62, 2001-01-01

    Japanese Society of Animal Science

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各種コード

  • NII論文ID(NAID)
    10008020599
  • NII書誌ID(NCID)
    AN00195188
  • 本文言語コード
    ENG
  • 資料種別
    ART
  • ISSN
    13443941
  • NDL 記事登録ID
    5646874
  • NDL 雑誌分類
    ZR22(科学技術--農林水産--畜産)
  • NDL 請求記号
    Z18-348
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
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