Morphological and Biochemical Changes Occurring during Cornea Development in Newborn Dogs

• ISHII Yoko

  Department of Veterinary Anatomy, Rakuno Gakuen University

• YAMAMOTO Etsuko

  Department of Veterinary Anatomy, Rakuno Gakuen University

• UEDA Hiromi

  Department of Veterinary Anatomy, Rakuno Gakuen University

• TAKEHANA Kazushige

  Department of Veterinary Anatomy, Rakuno Gakuen University

Bibliographic Information

Other Title

• イヌの角膜成熟に関する形態学的および生化学的解析
• イヌ ノ カクマク セイジュク ニ カンスル ケイタイガクテキ オヨビ セイカガクテキ カイセキ

Abstract

Turbidity of the cornea, in newborn puppies a mechanism for protecting the immature retinaand tapetum, parallels decrease in the density of the matrix and thickening and aligning of collagen fibrils. Biochemical analysis indicates a considerable increase in keratan sulfate and a decrease in dermatan sulfate during cornea development. Maintenance of collagen-fibril diameter and preservation of interstitial spaces seems to depend on the functioningof keratan sulfate. Dermatan, on the other hand, inhibits formation of collagen fibrils.Observation of these samples suggests that these two ground substances play essential roles in corneal maturation in neonatal dogs.

Journal

• Journal of the Japan Veterinary Medical Association

  Journal of the Japan Veterinary Medical Association 54 (11), 843-846, 2001

  Japan Veterinary Medical Association

Keywords

• collagen fiber
• cornea
• dermatan sulfate
• dog
• keratan sulfate

Details

• CRID: 1390282679683589376
• NII Article ID: 10008023884
• NII Book ID: AN00191857
• DOI: 10.12935/jvma1951.54.843
• COI: 1:CAS:528:DC%2BD38XitVSitQ%3D%3D
• ISSN: 21860211
• ISSN: 04466454
• NDL BIB ID: 5995117
• Web Site: https://agriknowledge.affrc.go.jp/RN/2030641098
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I5995117
• Web Site: https://search.jamas.or.jp/link/ui/2002122012
• Data Source:
  • JaLC
  • IRDB
  • NDL
  • Crossref
  • CiNii Articles
• Abstract License Flag: Disallowed