Near haploid核型を呈した成人急性リンパ芽球性白血病 Adult acute lymphoblastic leukemia presenting a near haploid karyotype
Thirty cases of childhood acute lymphoblastic leukemia (ALL) with a near haploid karyotype (<30 chromosomes) have been reported so far. However, despite a few cases of severely hypodiploid (30∼39 chromosomes) ALL, no near haploid cases have been reported in adult patients. Here, we describe a 64-year-old woman with ALL (L2, CD10<sup>+</sup> 19<sup>+</sup> 34<sup>+</sup> HLA-DR<sup>+</sup>) presenting a near haploid karyotype of 27, X, +X, +6, +10, +21/54, idem×2. She died of septic shock during complete remission 6.5 months after the diagnosis.
臨床血液 41(9), 764-767, 2000-09-30