Von Recklinghausen's Disease Complicated by Macroglobulinemia, Malignant Schwannoma and Pheochromocytoma.

DOI PubMed 2 Citations 5 References
  • KAMOSHITA Masaharu
    Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
  • SUZUKAWA Kazumi
    Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
  • KOBAYASHI Toshitaka
    Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
  • HASEGAWA Yuichi
    Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
  • SATOH Yuji
    Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
  • NINOMIYA Haruhiko
    Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
  • NAGASAWA Toshiro
    Division of Hematology, Institute of Clinical Medicine, University of Tsukuba
  • ABE Tsukasa
    Division of Hematology, Institute of Clinical Medicine, University of Tsukuba

Bibliographic Information

Other Title
  • マクログロブリン血症，悪性神経鞘腫，褐色細胞腫を合併したｖｏｎ　Ｒｅｃｋｌｉｎｇｈａｕｓｅｎ病

Search this article

Abstract

We reported a case of von Recklinghausen's disease complicated by macroglobulinemia, malignant Schwannoma and pheochromocytoma. A 43-year-old male patient who was diagnosed as von Recklinghausen's disease developed abdominal masses at 5 years after the adrenalectomy for pheochromocytoma. Computed tomography showed multiple heterogenous tumors in abdominal cavity. Histological examination of resected tumor was compatible with malignant Schwannoma. At the same time, peripheral blood and bone marrow smears showed a large number of plasmacytoid lymphocytes. Immunoelectrophoresis revealed M-protein of IgM, κ type. He was also diagnosed of coexistence with macroglobulinemia. The chemotherapeutic protocols used were not effective against both malignant Schwannoma and macroglobulinemia. The present case is a rare case of von Recklinghausen's disease associated with triple neoplasms.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 36 (1), 59-62, 1995

    The Japanese Society of Hematology

Citations (2)*help

See more

References(5)*help

See more

Keywords

Details 詳細情報について

Report a problem

Back to top