Improvement of Thrombocytopenia by Administration of M-CSF in a Patient with Relapsed Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia

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  • ENDO Akira
    The Second Department of Internal Medicine, Tottori University School of Medicine
  • TAJIMA Fumihito
    The Second Department of Internal Medicine, Tottori University School of Medicine
  • KAWATANI Toshio
    The Second Department of Internal Medicine, Tottori University School of Medicine
  • KAWASAKI Hironaka
    The Second Department of Internal Medicine, Tottori University School of Medicine

Bibliographic Information

Other Title
  • 血小板減少に対しマクロファージコロニー刺激因子(M-CSF)が有効であったPh<sup>1</sup>陽性急性リンパ性白血病再発例
  • 血小板減少に対しマクロファージコロニー刺激因子(M-CSF)が有効であったPh1陽性急性リンパ性白血病再発例
  • ケッショウバン ゲンショウ ニ タイシ マクロファージ コロニー シゲキ イン

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Abstract

A 55-year old male, diagnosed as Ph1 (+) ALL in July 1992, subsequently achieved complete remission. However, he was admitted again in November 1993 because of relapse. Although blasts in bone marrow decreased following chemotherapy and G-CSF administration, thrombocytopenia remained, and he needed platelet transfusions every other day. After he began receiving M-CSF, the platelet count increased and platelet transfusions became unnecessary. M-CSF may be useful for thrombocytopenia after chemotherapy in Ph1 (+) ALL.

Journal

  • Rinsho Ketsueki

    Rinsho Ketsueki 37 (9), 863-866, 1996

    The Japanese Society of Hematology

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