上部消化管に主座を有する悪性リンパ腫の治療 : 非切除治療法の成績について  [in Japanese] Evaluation of non-surgical therapy for the malignant lymphomas located mainly in stomach and duodenum  [in Japanese]

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Author(s)

    • 田利 晶 TARI Akira
    • 広島赤十字・原爆病院第6内科 Sixth Department of Internal Medicine of Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital
    • 麻奥 英毅 ASAOKU Hideki
    • 広島赤十字・原爆病院第4内科 4th Department of Internal Medicine of Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital
    • 谷 洋 TANI Hiroshi
    • 広島赤十字・原爆病院第7内科 7th Department of Internal Medicine of Hiroshima Red Cross Hospital and Atomic-Bomb Survivors HospitalV
    • 柏戸 宏造 KASHIWADO Kouzou
    • 広島赤十字・原爆病院放射線科 Department of Radiology of Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital
    • 栗原 寛治 KURIHARA Kanji
    • 広島赤十字・原爆病院病理部 Departmento of Pathology of Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital
    • 藤原 恵 FUJIHARA Megumu
    • 広島赤十字・原爆病院病理部 Departmento of Pathology of Hiroshima Red Cross Hospital and Atomic-Bomb Survivors Hospital

Abstract

胃・十二指腸に病変の主座を有する悪性リンパ腫(非ホジキンリンパ腫)29例を対象として,非切除治療法の効果を検討した.MALTリンパ腫を含むStageI~IIIの症例に対しては,<I>Helicobacter pylori</I>除菌,化学療法,放射線療法を組み合わせることにより完全寛解に導入することができ,他病死例3例以外は寛解を維持しこれらの症例では本治療法で寛解に導入できると考えられた.StageIVの症例に対しても,5096の症例では化学療法により完全寛解に導入することができた.本検討成績から,現在我々の施行している胃・十二指腸原発悪性リンパ腫に対する非切除根治治療は,患者のQOLを保ちかつ極めて有効であると考えられた.

We evaluated the effects of the conservative treatmet to 29 patients with non-Hodgkin lymphomas located mainly in stomach and duodenum. We could induce complete remission in all the cases of stage I, II, and III including MALT lymphomas by the combination therapy of <I>Helicobacter pylori</I> (<I>H. pylori</I>) eradication, chemotherapy, and radiation, and the complate remission persisted in all except for the three cases who died of other causes. Even in stage IV lymphomas mainly located in stomach and duodenum, we could induce complete remission in 50% of them. Considering the quality of life of patients with lymphomas located mainly in stomach and duodenum, the conservative treatment may be of benefit more than the surgical approach.

Journal

  • Nippon Shokakibyo Gakkai Zasshi

    Nippon Shokakibyo Gakkai Zasshi 98(10), 1154-1163, 2001-10-05

    The Japanese Society of Gastroenterology

References:  24

Cited by:  1

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