口蓋扁桃癌のアポトーシス  [in Japanese] Apoptosis in Palatine Tonsil Carcinomas  [in Japanese]

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Author(s)

Abstract

Apoptosis was observed in palatine tonsil carcinomas (squamous cell carcinoma; 11 cases) by TUNEL staining. The TUNEL labeling index (TLI) of carcinoma cells had no relation to TNM, staging, pathohistological differentiated grades or the efficiency of radiotherapy. TLI (means: 5.2%) of postradiotherapy cases was higher than that of preradiotherapy cases (1.9%). TUNEL positive cells were found in the tissues surrounding cancers. In the surrounding tissues, the TLI (means: 5.1%) of postradiotherapy cases was higher than that of preradiotherapy cases (2.0%). These findings indicated that apoptosis induced by radiotherapy could suppress cancer development. Reversely, the invasion and metastasis of surviving cancers may be promoted by apoptosis induced in the surrounding tissues.

Journal

  • Practica Oto-Rhino-Laryngologica

    Practica Oto-Rhino-Laryngologica 94(6), 531-535, 2001-06-01

    The Society of Practical Otolaryngology

References:  14

Codes

  • NII Article ID (NAID)
    10008096768
  • NII NACSIS-CAT ID (NCID)
    AN00107089
  • Text Lang
    JPN
  • Article Type
    NOT
  • ISSN
    00326313
  • Data Source
    CJP  J-STAGE 
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