上咽頭癌10年間の治療成績  [in Japanese] Clinical Outcome of 19 Patients with Nasopharyngeal Cancer ; A Review of Neo-Adjuvant Chemotherapy  [in Japanese]

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Author(s)

Abstract

We clinically examined 19 cases of nasopharyngeal cancer in which primary care was administered in the Department of Otolaryngology, Tokyo Metropolitan Fuchu Hospital between September 1990 and August 1999. The subjects consisted of 11 males and 8 females. Histophathological study revealed 17 cases of WHO type III tumors (14 cases were poorly differentiated squamous cell carcinoma and 3 cases were lymph-epithelioma). The accumulated 5-year survival rate by the Kaplan-Meier method was 50% in T1, 75% in T2, 0% in T4, and 36% overall. Neo-adjuvant chemotherapy was administered in 15 cases and distant metastasis appeared in 3 cases (21%) after definitive radiotherapy. The biological characteristic of WHO type TIE tumors is a tendency towards early metastasis, and we speculated that this might be the cause of the lower level of effectiveness of the neo-adjuvant chemotherapy in these cases. At present, this therapy is not effective and further improvement is required.

Journal

  • Practica Oto-Rhino-Laryngologica

    Practica Oto-Rhino-Laryngologica 94(7), 605-609, 2001-07-01

    The Society of Practical Otolaryngology

References:  12

Cited by:  5

Codes

  • NII Article ID (NAID)
    10008096958
  • NII NACSIS-CAT ID (NCID)
    AN00107089
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    00326313
  • Data Source
    CJP  CJPref  J-STAGE 
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