スギ花粉症自己診断例のアレルゲン陽性率 Positive Rate of CAP-RAST in 299 Cases of Suspected Japanese Cedar Pollinosis
It is important to determine the allergen for treatment and prevention in allergic diseases, especially pollinosis. However, few patients have their specific allergen determined prior to treatment. In this study, we investigated the positive rate of specific IgE in 299 patients with suspected Japanese cedar pollinosis. Ten allergens were tested using CAP-RAST in 299 subjects consisting of 175 males and 124 females who visited the OCROM clinic (Suita city). The positive rate was 78.9% for Japanese cedar, 52.5% for D1, 50.8% for D2, 50.5% for HD1, 48.5% for Japanese cypress and 44.1% for orchard grass. About 60% of the patients who were positive for Japanese cedar also showed positive for Japanese cypress. However, no patients were positive for Japanese cypress and negative for Japanese cedar. There were no correlations between positivity rates and age for Japanese cedar. However, in HD1, the positive rate in younger patients was higher than in older patients. The numbers of simultaneously positive allergens was 4.5 in patients under 20 and gradually decreased according to age. It was very interesting that 2 patients were positive only for birch pollen and in these cases, it was very difficult to decide whether the patients had Japanese cedar pollinosis. Based on these results, we suggest that it is necessary to determine the specific allergen before treatment or prevention.
耳鼻咽喉科臨床 94(12), 1073-1078, 2001-12-01