突発性難聴300耳の治療に関する検討 : Grade 2-4 における多剤併用効果  [in Japanese] A Study of Therapy Used for 300 Patients with Sudden Deafness : The Combination Effects in Grades 2-4  [in Japanese]

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Author(s)

Abstract

We investigated the therapy used in 300 patients with sudden deafness who were treated at Hakodate Municipal Hospital, Ebetsu Municipal Hospital, Obihiro Kousei Hospital and Nakamura Memorial Hospital in the period 1994-2000. The grades were 1, 2, 3 and 4 in approximately 22, 30, 35and14%, respectively. General improvement was achieved in 78% of the subjects (Grades1-4). The use of pentoxyfilline (n=25), oxygen under high pressure (OHP) (n=63) and lipo-prostaglandin E1 (lipo-PGE1) (n=27) resulted in significant (p<0.05) improvements in patients with sudden deafness (Grades2-4) when applied in combination with steroids, VB12 and Adenosinetriphosphate disodium. The improvement rate was 92, 86 and 100% in the pentoxyferin, OHP and lipo-PGEl groups, respectively.<br>These findings suggest that the improvement of blood flow in the inner ear may be very important in treating sudden deafhess.

Journal

  • Practica Oto-Rhino-Laryngologica

    Practica Oto-Rhino-Laryngologica 95(2), 123-129, 2002-02-01

    The Society of Practical Otolaryngology

References:  33

Cited by:  7

Codes

  • NII Article ID (NAID)
    10008098869
  • NII NACSIS-CAT ID (NCID)
    AN00107089
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    00326313
  • Data Source
    CJP  CJPref  J-STAGE 
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