書誌事項
- タイトル別名
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- Blood Gas Changes in Duchenne Type Muscular Dystrophy.
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We studied changes in blood gas data from 32 patients with Duchenne type muscular dystrophy (DMD), who were followed for more than 5 years. Regression lines for each blood gas variable were obtained by the least square regression method, from 276 observations. The mean change per year was calculated by averaging the individual slolpes.<br>All blood gas variables (PaO<sub>2</sub>, PaCO<sub>2</sub>, pH, and [HCO3-]) correlated significantly with age the regression lines were:<br>PaO<sub>2</sub>=95.6-0.45×Age, PaCO<sub>2</sub>=34.7+0.70×Age, pH=7.397-0.0023× Age, [HCO3-]=20.7+0.28×Age.<br>The rates of change were-0.74 Torr/year for PaO<sub>2</sub>, 1.07 Torr/year for PaCO<sub>2</sub>, -0.0028 per year for pH and 0.55mEq/l/year for [HCO3-]. The slope of each regression line was within the average individual yearly change±one standard deviation. AaDo2 did not change significantly with age, but chronic respiratory acidosis worsened because of alveolar hypoventilation.<br>As an index of the severity of DMD, PaCO<sub>2</sub> was better than PaO<sub>2</sub>, because the former was more strongly correlated with age and the values of PaCO<sub>2</sub> deviated less from the regression line.
収録刊行物
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- 日本胸部疾患学会雑誌
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日本胸部疾患学会雑誌 33 (1), 17-22, 1995
社団法人 日本呼吸器学会
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詳細情報 詳細情報について
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- CRID
- 1390282679993355520
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- NII論文ID
- 130003678677
- 10008106300
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- NII書誌ID
- AN00187758
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- ISSN
- 1883471X
- 03011542
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- 本文言語コード
- ja
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- データソース種別
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- JaLC
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可
