A Case of Chronic Eosinophilic Pneumonia Involving IL-5 and GM-CSF.

DOI PubMed 5 Citations 8 References
  • Momose Tomoyasu
    The First Department of Internal Medicine, Shinshu University School of Medicine
  • Okubo Yoshio
    The First Department of Internal Medicine, Shinshu University School of Medicine
  • Takeda Masashi
    The First Department of Internal Medicine, Shinshu University School of Medicine
  • Fujimoto Keisaku
    The First Department of Internal Medicine, Shinshu University School of Medicine
  • Honda Takavuki
    The First Department of Internal Medicine, Shinshu University School of Medicine
  • Sekiguchi Moriei
    The First Department of Internal Medicine, Shinshu University School of Medicine

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  • 気管支肺胞洗浄液及び血清中にＩＬ‐５，ＧＭ‐ＣＳＦを認めた慢性好酸球性肺炎の１例

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Abstract

A 57-year-old woman was admitted because of dry cough and middle-grade fever. Chest rentogenogram showed a diffuse infiltrative shadow in the right middle and lower lung fields. The symptoms disappeared after treatment with minocycline, but a new dense shadow appeared in the right upper and middle lung fields. Eosinophilic pneumonia was diagnosed from the results of bronchoalveolar lavage and transbronchial lung biopsy. The symptoms were alleviated and the infiltrative shadow was effaced after treatment with predonisolone (40mg/day). The results of a bioassy with human eosinophils suggested that the serum and bronchoalveolar lavage fluid contained IL-5 and GM-CSF.

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