A Case of Large Cell Carcinoma of the Lung Arising from the Inner Surface of a Pulmonary Bulla and Complicated by Hematoma.

  • Sakamaki Fumio
    Department of Medicine, School of Medicine, Keio University
  • Nakano Masaru
    Department of Medicine, School of Medicine, Keio University
  • Urano Tetsuya
    Department of Medicine, School of Medicine, Keio University
  • Mori Masaaki
    Department of Medicine, School of Medicine, Keio University
  • Yamaguchi Kazuhiro
    Department of Medicine, School of Medicine, Keio University
  • Kanazawa Minoru
    Department of Medicine, School of Medicine, Keio University
  • Izumi Yotaro
    Department of Surgery, Keio University, Central Clinical Laboratories, Keio University Hospital
  • Kikuchi Koji
    Department of Surgery, Keio University, Central Clinical Laboratories, Keio University Hospital
  • Kobayashi Koichi
    Department of Surgery, Keio University, Central Clinical Laboratories, Keio University Hospital
  • Kuramochi Shigeru
    Division of Surgical Pathology, Central Clinical Laboratories, Keio University Hospital

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Other Title
  • ブラ内に血腫を伴ったブラ壁発生の肺大細胞癌の1例

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Abstract

A 64-year-old man with a history of smoking was admitted to our hospital, because he was noted to have a solitary mass lesion at the apex of the right lung on a chest roentgenogram. Eight months before admission, he had come to our hospital because of hemoptysis. At that time, however, no abnormal shadow was seen on his chest roentgemogram, except for multiple bullae at both apexes. Based on chest CT findings on admission, the tumor appeared to be a hematoma growing inside the bulla. The resected tumor was found to contain a large amount of coagulated blood in the bulla. Histopathological examination of the bulla revealed a proliferation of large atypical cells from the inner surface of the bulla toward the inner space. Thus, the diagnosis was large cell carcinoma within the wall of the pulmonary bulla, the inside of which was filled with hematoma. We believe that the hematoma in the bulla allowed us to make an early diagnosis, and thus to succeed in curing the patient.

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