Acute Lupus Pneumonitis Presenting as Multiple Nodular Shadows.

  • Kawasaki Akira
    First Department of Internal Medicine, Toyama Medical and Pharmaceutical University
  • Ohtatsu Rika
    First Department of Internal Medicine, Toyama Medical and Pharmaceutical University
  • Kashii Tatsuhiko
    Department of Internal Medicine, Takagi General Hospital
  • Hayase Mitsuru
    Department of Internal Medicine, Takagi General Hospital
  • Mizushima Yutaka
    First Department of Internal Medicine, Toyama Medical and Pharmaceutical University
  • Kobayashi Masashi
    First Department of Internal Medicine, Toyama Medical and Pharmaceutical University
  • Kitagawa Masanobu
    First Department of Pathology, Toyama Medical and Pharmaceutical University

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Other Title
  • 多発性結節性陰影を伴った急性ループス肺炎の1例

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Abstract

A 24-year-old woman consulted a physician because of fever, dry cough, and arthralgia of one month duration. She was transferred to our hospital for more detailed examination of pancytopenia and diffuse infiltrative shadows on a chest X-ray film. On admission she was depressed, and had oral ulcers. Pleural and pericardial effusions were observed. Laboratory studies were positive for anti-nuclear antibody, anti-DNA antibody, and lupus erethymatosus. Casts were found in the urine, and systemic lupus erythematosus was diagnosed. Chest radiography and CT scan showed nodular shadows in the right S8 (2nodules with 1cm diameter) (1cm×2), right S10 (0.5cm diameter), and left S8 (0.5cm diameter) regions, as well as diffuse infiltrative shadows in both lower lung fields. A specimen obtained by transbronchial lung biopsy revealed acute interstitial pneumonia with arteritis. After treatment with prednisolone (60mg/day), the nodular and infiltrative shadows rapidly disappeared. Cases of lupus pneumonitis presenting as noduar shadows are very rare and are valuable in diagnostic imaging.

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