肺気腫患者における高分解能 CT と^<99m>Tc-technegas SPECT の領域別比較検討  [in Japanese] Comparison between High-Resolution Computed Tomography and ^<99m>Tc-technegas SPECT Pulmonary Emphysema  [in Japanese]

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Abstract

最近利用可能となった<sup>99m</sup>Tc-テクネガス換気シンチグラフィは他の換気シンチに比べ緊急時にも利用可能で, またSPECTに適しているとされている. 肺気腫患者においてテクネガスにおける換気異常は高分解能CT (以下HRCT) における形態の異常より早期に検出可能との報告もある. 今回我々は肺気腫患者15例において両肺を, 右上葉・中葉・下葉・左上区・舌区・下葉の6つの領域に分け, <sup>99m</sup>Tc-テクネガス換気SPECTとHRCTによる所見を領域別に比較検討した. 小葉中心性肺気腫はテクネガス, HRCTともに下肺に比べ上肺の所見が強い傾向が見られた. テクネガスのみで異常所見の見られる領域もあった. 汎小葉性肺気腫ではテクネガスで下葉に強い変化が見られ, HRCTに比べ異常の指摘が容易であった. <sup>99m</sup>Tc-テクネガス換気SPECTは肺気腫患者において初期変化や汎小葉性変化の検出に有用であった.

Scintigraphy with <sup>99m</sup>Tc-technegas was recently introduced for clinical imaging of lung ventilation. This method has been found to be useful in emergencies, to be more suitable for single photon emission computed tomography (SPECT) than other agents used in ventilation Scintigraphy, and could reveal abnormalities in ventilation more easily than high resolusion computed tomography (HRCT) in pulmonary emphysema. We compared <sup>99m</sup>Tc-technegas SPECT with HRCT in six regions: the right upper, middle, and lower lobes, the left upper lobe, the lingula, and the left lower lobe, in 15 patients with pulmonary emphysema. Patients with centrilobular emphysema tended to show stronger changes in upper lobes than in lower lobes on both <sup>99m</sup>Tc-technegas SPECT and HRCT. Some regions showed no change on HRCT but various changes on <sup>99m</sup>Tc-SPECT. Patients with panlobular emphysema showed severe changes on <sup>99m</sup>Tc-SPECT in lower lung fields in which well-demarcated areas of low attenuation were not seen on HRCT. We conclude that <sup>99m</sup>Tc-SPECT is useful for detecting early changes and panlobular changes in pulmonary emphysema.

Journal

  • The Japanese journal of thoracic diseases

    The Japanese journal of thoracic diseases 34(5), 511-519, 1996-05-25

    The Japanese Respiratory Society

References:  15

Cited by:  3

Codes

  • NII Article ID (NAID)
    10008109721
  • NII NACSIS-CAT ID (NCID)
    AN00187758
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    03011542
  • Data Source
    CJP  CJPref  J-STAGE 
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