サイトメガロウイルス単核球症にサイトメガロウイルス肺炎を合併したと考えられる1例  [in Japanese] Cytomegalovirus Mononucleosis with Cytomegalovirus Pneumonia in a Health Adult  [in Japanese]

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Abstract

症例は29歳女性. 発熱, 咽頭痛にて発症し, 発症6日後に発疹, 10日後に乾性咳嗽を伴うようになる. 胸部レントゲン写真上明らかな陰影は認めなかったが, 胸部CT上肺野濃度の上昇を認め<sup>67</sup>Ga scintigram でも両肺野に異常集積を認めた. CMV-IgM抗体が高値を示し, CMV単核球症と診断した. BALF中のCMV-DNAを polymerase chain reaction method (PCR法) を用いて検出することができ, CMV肺炎を合併したと考えられた. BALF中のCMVを証明し得たCMV単核球症の報告は無く興味深い1例と考えた.

A 29-year-old woman developed fever and sore throat 14 days before admission. Six days later she noted the onset of a rash and ten days later she noted a dry cough. The chest X-ray film showed no abnormal shadow, but a chest CT scan showed a diffuse ground-glass shadow and a <sup>67</sup>Ga-scintigram showed abnormal lung uptake. The level of anti-cytomegalovirus antibody of the IgM class was high; cytomegalovirus mononucleosis was diagnosed and cytomegalovirus pneumonia was suspected. Cytomegalovirus DNA was detected in bronchoalveolar lavage fluid by the polymerase chain reaction method. We known of no previously reported case of cytomegalovirus mononucleosis in which cytomegalovirus DNA was found in bronchoalveolar lavage fluid by the polymerase chain reaction method.

Journal

  • The Japanese journal of thoracic diseases

    The Japanese journal of thoracic diseases 34(6), 726-730, 1996-06-25

    The Japanese Respiratory Society

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