副鼻腔気管支症候群との鑑別が困難であった Good 症候群の1例  [in Japanese] Immunodeficiency with Thymoma (Good's Syndrome) Similar to Sino-bronchial Syndrome  [in Japanese]

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Abstract

症例は58歳, 男性. 三年前より反復する気道感染のため当科を紹介され受診した. 低γグロブリン血症を認め, 精査の結果, 胸腺腫に伴う原発性免疫不全症 (Good症候群) と診断した. 本例は胸腺腫摘出後, 外来にて定期的にγグロブリン製剤補充療法を行っているが気道感染の再発, 増悪は認めていない. 本症例のように胸腺腫の合併した免疫不全例は本邦では比較的稀で, 特に胸部単純レントゲン写真上, 腫瘤陰影を明らかにし得ないときは, X線写真上は副鼻腔気管支症候群, また低γグロブリン血症からは Common variable immunodeficiency (CVI) などの反復性感染をきたしうる疾患との注意深い鑑別診断が必要と考えられる.

A 58-year-old man was admitted to our hospital because of recurrent pulmonary infections that began three years previously. Laboratory data showed hypogammaglobulinemia and a chest computed tomogram showed diffuse bilateral micronodular shadows and an anterior mediastinal tumor. Immunodeficiency with thymoma (Good's syndrome) was diagnosed. After undergoing a thymectomy, he received intravenous γ-globulin injections once a month for prophylaxis.<br>Good's syndrome occurs rarely in Japan. A solid tumor-like shadow is not necessarily observed in routine chest X-ray studies, and hypogammaglobulinemia is one sign of this syndrome. The hypogammaglobulinemia of Good's syndrome should be carefully differentiated from that of other immunodeficiency diseases such as common variable immunodeficiency, the aquired immunodeficiency syndrome, chronic lymphocytic leukemia, non-Hodgkin's lymphoma, and multiple myeloma (non-secretory type).

Journal

  • The Japanese journal of thoracic diseases

    The Japanese journal of thoracic diseases 34(7), 829-832, 1996-07-25

    The Japanese Respiratory Society

References:  10

Cited by:  3

Codes

  • NII Article ID (NAID)
    10008110573
  • NII NACSIS-CAT ID (NCID)
    AN00187758
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    03011542
  • Data Source
    CJP  CJPref  J-STAGE 
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