呼吸同調型酸素供給調節器をとおした経鼻酸素吸入による鼻腔クリアランスの影響

• 中村 清一

  都立広尾病院呼吸器科

• 森 豊

  都立広尾病院呼吸器科

• 滝沢 潤

  都立広尾病院呼吸器科

• 川上 雅彦

  都立広尾病院呼吸器科

書誌事項

タイトル別名

• Effect of On-demand Inhalation of Dry Oxygen on Nasal Mucociliary Clearance.

抄録

Aim: To determine whether nasal mucociliary clearance is affected by dry oxygen delivered on demand.<br>Methods: Saccharin nasal transit time was measured as an index of nasal mucociliary clearance. One group of patients was given dry oxygen via a nasal cannula and a demand delivery system, and another group was given dry oxygen by continuous inhalation. In each group, continuous inhalation of humidified oxygen seved as the control. Saccharin transit time was measured before and after 8 hours of oxygen inhalation.<br>Subjects: The subjects were 25 patients with chronic respiratory failure who were receiving home oxygen therapy via nasal cannula. All the subjects were clinically stable (age 72±1, mean±SE), %VC 46.6±3.0, FEV₁/FVC% 9.0±4.5, PaO₂ 55.7±2.0Torr, PaCO₂ 53.9±1.9Torr).<br>Results: Saccharin transit time after inhalation of dry oxygen on demand did not differ from that after continuous inhalation of humidified oxygen (15.6±1.5 vs 14.9±1.4min). Saccharin transit time after continuous inhalation of dry oxygen was significantly lower than that after continuous inhalation of humidified oxygen (26.6±5.4 vs 16.7±2.6min, p<0.05).<br>Conclusion: We conclude that using the demand oxygen delivery system with a nasal cannula for 8 hours had no adverse effects on nasal mucociliary clearance.

収録刊行物

• 日本胸部疾患学会雑誌

  日本胸部疾患学会雑誌 34 (11), 1189-1193, 1996

  社団法人 日本呼吸器学会

キーワード

• 慢性呼吸不全
• 携帯用酸素ボンベ
• 呼吸同調型酸素供給調節器
• 鼻粘液線毛クリアランス
• サッカリンテスト

詳細情報

• CRID: 1390282679994135808
• NII論文ID: 130003678910
• NII論文ID: 10008111413
• NII書誌ID: AN00187758
• DOI: 10.11389/jjrs1963.34.1189
• ISSN: 1883471X
• ISSN: 03011542
• PubMed: 8976072
• Web Site: https://search.jamas.or.jp/link/ui/1997111327
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • PubMed
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可