Summer-Type Hypersensitivity Pneumonitis in a Family.

• Kawayama Tomotaka

  Department of Respiratory Disease, Sent Marry's Hospital

• Shigematsu Hiromichi

  Department of Respiratory Disease, Sent Marry's Hospital

• Kawaguchi Sinzo

  Department of Respiratory Disease, Sent Marry's Hospital

• Kawahara Masao

  Department of Respiratory Disease, Sent Marry's Hospital

• Oizumi Kotaro

  First Department of Internal Medicine, Kurume University School of Medicine

Bibliographic Information

Other Title

• 家族内発生をみた夏型過敏性肺臓炎例

Abstract

We encountered a family in which three of the five members (The parents and a daughter) had summer-type hypersensitivity pneumonitis that occurred in late summer. All three patients had a productive cough and shortness of breath. Chest roentgenograms of the mother and daughter (but not the father) showed diffuse small nodular shadows in both lung fields. Examination of bronchalveolar lavage fluid from all three patients showed very high total cell counts, high percentages of T lymphocytes, and low ratios of CD4+-to-CD8+ cells. Microscopic examination of transbronchial biopsy specimens obtained from the daughter revealed infiltration of mononuclear cells with characteristic Masson bodies in alveolar septa, and gramulomas in the interstitium. Both mother and daughter were positive for serum anti- Trichosporon cutaneum (serotype II) antibody, but the father, who was a current smoker, was not. Thus, both mother and daughter were given the diagnosis of summer-type hypersensitivity pneumonitis, and in the father that diagnosis was strongly suspected.

Journal

• The Japanese journal of thoracic diseases

  The Japanese journal of thoracic diseases 34 (12), 1401-1405, 1996

  The Japanese Respiratory Society

Keywords

• Summer-type hypersensitivity pneumonitis
• Familial occurrence
• HLA-antigen
• <i>Trichiosporon cutaneum</i>

Details

• CRID: 1390282679996183040
• NII Article ID: 10008111975
• NII Book ID: AN00187758
• DOI: 10.11389/jjrs1963.34.1401
• ISSN: 1883471X
• ISSN: 03011542
• PubMed: 9022328
• Web Site: https://search.jamas.or.jp/link/ui/1997184564
• Text Lang: ja
• Data Source:
  • JaLC
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed