Spontaneous Recovery from Cytomegalovirus Pneumonia.

  • Matsuki Hiroaki
    Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
  • Kuwano Kazuyoshi
    Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
  • Yoshimi Michihiro
    Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
  • Nomoto Yoshitsugu
    Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
  • Kunitake Ritsuko
    Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
  • Hagimoto Naoki
    Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University
  • Hara Nobuyuki
    Research Institute for Diseases of the Chest, Faculty of Medicine, Kyushu University

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  • 自然治癒と考えられるSLEに合併したサイトメガロウイルス肺炎の1例

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Abstract

A 30-year-old woman with systemic lupus erythematosus was admitted to our hospital because of a slight fever and diffuse interstitial shadows on a chest X-ray film. She had taken prednisolone (60mg per day) at another hospital for six weeks. At the time of admission to our hospital, she had been treated with antituberculosis drugs (streptomycin, isoniazid, and rifampicin) for two weeks because of suspected miliary tuberculosis. Chest radiography on admission revealed diffuse nodular and micronodular shadows in the middle and lower lung fileds on both sides. Examination of transbronchial lung biopsy specimens revealed intranuclear viral inclusion bodies in infected alveolar epithelial cells, which suggested the diagnosis of cytomegalovirus infection. The elevation of serum IgM antibody to cytomegalovirus and positive resutls of in situ hybridization for cytomegalovirus DNA supported this diagnosis. The symptoms and radiographic abnormalities resolved completely without ganciclovir. Although we cannot exclude the possibility that the antituberculosis drugs caused the resolution of the cytomegalovirus pneumonia, it appears most probable that the cytomegalovirus pneumonia resolved spontaneously.

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