定量的PCRによる新しい遺伝子発現プロファイルシステムの構築 : 臨床および創薬への応用 [in Japanese] A novel gene expression profiling system using quantitative PCR. For clinical research and drug development.:A navel gene expression profiling system using quantitative PCR—For clinical research and drug development [in Japanese]
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Innovation of gene technologies such as DNA microarray and real-time PCR has made it possible to quantitatively measure the expression of multiple genes. Such new technologies are expected to advance clinical medicine and pave new avenues for drug development. Source Precision Medicine<SUP>TM</SUP>, a biotechnology company with which we have been working, has recently established a novel gene-expression profiling system using quantitative PCR in order to construct data bases of genetic profiles of individual patients upon therapy and disease progression. We here describe the system and recent data of the gene profiles associated with inflammatory processes, and discuss advantages of the use of the system for diagnosis/therapy and drug development.
- Drug Delivery System
Drug Delivery System 17(2), 119-126, 2002-03-10
THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM