銀系無機抗菌剤の歯科材料への応用 : Streptococcus mutansに対する抗菌作用  [in Japanese] Application of Silver-Inorganic Antimicrobial Reagent for Dental Materials : Antimicrobial Action for Streptococcus mutans  [in Japanese]

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Author(s)

    • 田中 孝明 TANAKA Takaaki
    • 日本大学松戸歯学部第2歯科補綴学教室 Department of Crown and Bridge Prosthodontics, Nihon University School of Dentistry at Matsudo
    • 水川 一廣 MIZUKAWA Kazuhiro
    • 日本大学松戸歯学部第2歯科補綴学教室 Department of Crown and Bridge Prosthodontics, Nihon University School of Dentistry at Matsudo
    • 志田 耕一郎 SHIDA Kouichirou
    • 日本大学松戸歯学部第2歯科補綴学教室 Department of Crown and Bridge Prosthodontics, Nihon University School of Dentistry at Matsudo
    • 小林 平 KOBAYASHI Taira
    • 日本大学松戸歯学部第2歯科補綴学教室 Department of Crown and Bridge Prosthodontics, Nihon University School of Dentistry at Matsudo
    • 妻鹿 純一 MEGA Junichi
    • 日本大学松戸歯学部障害者歯科学教室 Department of Dentistry for the Handicapped, Nihon University School of Dentistry at Matsudo

Abstract

Recently, the concept of hygiene has been promoted, and many sanitary goods that contain antimicrobial reagents have been produced. Such reagents are divided into organic and inorganic ones. Some literature has pointed out that these reagents have many disadvantages, such as short-time durability of antibacterial effect, degeneration by heating operation, and physical irritation. Furthermore, the organic antimicrobial reagents have intensive antimicrobial action, but long use of these reagents may cause microbial substitution and teratogenicity.<BR>We aimed to put inorganic antimicrobial reagent into practical use, and the effects of silver-inorganic antimicrobial reagents (IONPURE<SUP>TM</SUP> and NOVARON AG 300<SUP>TM</SUP>) on oral microorganisms were examined.<BR>1. Minimum inhibitory concentrations (MICs) of antimicrobial reagents (IONPURE and NOVARON) for <I>Streptococcus mutans</I> were 7.5 mg/m/ and 1.3 mg/m/. The antimicrobial action was bacteriostatic. The microorganisms on resin plates that contained both antimicrobial reagents were remarkably reduced.<BR>2. MICs for <I>Streptococcus mutans</I> on resin plates that contained antimicrobial reagents were 5 wt%(IONPURE) and 10 wt%(NOVARON).<BR>3. Insoluble glucan synthesis was inhibited on NOVARON-containing resin plates. On the other hand, IONPURE was not so noticeable.<BR>4. The surviving microorganisms of <I>Streptococcus mutans</I> on resin plates that contained both antimicrobial reagents (3 wt%) were remarkably decreased.<BR>These results suggest that IONPURE and NOVARON were effectual antimicrobial reagents against <I>Streptococcus mutans</I>, and that they were useful for antimicrobial prosthesis.

Journal

  • Nihon Hotetsu Shika Gakkai Zasshi

    Nihon Hotetsu Shika Gakkai Zasshi 44(5), 651-657, 2000-10-10

    Japan Prosthodontic Society

References:  33

Cited by:  1

Codes

  • NII Article ID (NAID)
    10008156232
  • NII NACSIS-CAT ID (NCID)
    AN00197911
  • Text Lang
    JPN
  • Article Type
    Journal Article
  • ISSN
    03895386
  • Data Source
    CJP  CJPref  J-STAGE 
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