Antibacterial Effect of Dentine Primer Incorporating Antibacterial Monomer MDPB After Curing.

• Imazato Satoshi

  Department of Operative Dentistry, Osaka University Faculty of Dentistry

• Kobayashi Kyoko

  Department of Operative Dentistry, Osaka University Faculty of Dentistry

• Ehara Atsushi

  Department of Operative Dentistry, Osaka University Faculty of Dentistry

• Torii Mitsuo

  Department of Operative Dentistry, Osaka University Faculty of Dentistry

Bibliographic Information

Other Title

• 抗菌性モノマー含有プライマーに関する研究　（第２報）　ＭＤＰＢ配合プライマーの硬化後の抗菌性
• MDPB配合プライマーの硬化後の抗菌性

Abstract

The purpose of this study was to investigate the antibacterial effect after curing of dentine primer incorporating antibacterial monomer methacryloyloxydodecylpyridinium bromide (MDPB). Cured specimens were fabricated in the mould with 5% MDPB-containing primer or control primer, adhesive, and composite. Elution of antibacterial components and inhibitory effect against bacterial growth of cured specimen were determined by agar disc diffusion method. Bactericidal activity of cured primer was evaluated by counting the number of Streptococcus mutans after contact with the specimen for 1 hour and the elution of uncured MDPB was measured. Although experimental and control primers produced no inhibition zones against Streptococcus mutans and Lactobacillus casei, bacterial growth on agar under specimen of MDPB-containing primer was inhibited compared with controls. Both primer produced inhibition zones against Actinomyces viscosus, the size of halo by experimental primer being greater than control. Significantly less bacteria was recovered after contact with experimental primer compared with control, but elution of uncured MDPB was less than the minimum inhibitory concentration value. It can be concluded that dentine primer incorporating MDPB shows inhibitory and bactericidal activity which depend upon immobilized agent even after curing, although a small amount of uncured MDPB eluted also may somewhat inhibit susceptible species such as Actinomyces viscosus.

Journal

• Adhesive Dentistry

  Adhesive Dentistry 14 (3), 157-163, 1996

  Japan Society for Adhesive Dentistry

Keywords

• dentine primer
• antibacterial activity
• antibacterial monomer
• curing

Details

• CRID: 1390282679324733184
• NII Article ID: 130004047836
• NII Article ID: 10008176511
• NII Book ID: AN10044236
• DOI: 10.11297/adhesdent1983.14.157
• ISSN: 21859566
• ISSN: 09131655
• Web Site: https://search.jamas.or.jp/link/ui/1997007841
• Text Lang: ja
• Data Source:
  • JaLC
  • CiNii Articles
• Abstract License Flag: Disallowed