Molecular Basis of Spatio-temporal Dynamics in Inositol 1,4,5-Trisphosphate-Mediated Ca^<2+> Signalling

この論文にアクセスする

この論文をさがす

著者

抄録

Inositol 1, 4, 5−trisphosphate(IP<SUB>3</SUB>)−mediated Ca<SUP>2+</SUP> signalling regulates many important cell functions, and the spatio−temporal dynamics of the Ca<SUP>2+</SUP> signalling is a crucial factor for its versatility.The molecular mechanisms that control Ca<SUP>2+</SUP> signalling are now being investigated, and I here describe the subtypes of IP<SUB>3</SUB> receptors that have distinct functional properties and contribute to the diversity of Ca<SUP>2+</SUP> signalling patterns.I also discuss the spatio−temporal dynamics of intracellular IP<SUB>3</SUB> concentration, describing recent methodological advances in monitoring intracellular IP<SUB>3</SUB> concentration.These findings highlight the potential importance of the spatio−temporal information of any signalling molecule.

収録刊行物

  • The Japanese journal of pharmacology

    The Japanese journal of pharmacology 82(1), 15-20, 2000-01-01

    公益社団法人 日本薬理学会

参考文献:  41件中 1-41件 を表示

被引用文献:  2件中 1-2件 を表示

各種コード

  • NII論文ID(NAID)
    10008182507
  • NII書誌ID(NCID)
    AA00691188
  • 本文言語コード
    ENG
  • 資料種別
    REV
  • ISSN
    00215198
  • NDL 記事登録ID
    4966407
  • NDL 雑誌分類
    ZS51(科学技術--薬学)
  • NDL 請求記号
    Z53-D199
  • データ提供元
    CJP書誌  CJP引用  NDL  J-STAGE 
ページトップへ