Prospects for Gene-Based Immunopharmacology in Salivary Glands

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Author(s)

    • Yamano Seiichi YAMANO Seiichi
    • Gene Therapy and Threapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health
    • Baum Bruce J. BAUM Bruce J.
    • Gene Therapy and Therapeutics Branch, National Institute of Dental and Craniofacial Research, National Institutes of Health

Abstract

The clinical potential of gene transfer is increasing.One likely major application of this emerging biotechnology will be for gene therapeutics, the use of a gene as a drug.Salivary glands provide an unusual but increasingly valuable target site for gene transfer.Studies in animal salivary glands from several laboratories, including our own, have provided proof of this concept.In this review, we provide a background and perspective on possible strategies for gene-based immunopharmacology in salivary glands.We use as a target disease model the autoimmune exocrinopathy Sjögren’s syndrome.

Journal

  • The Japanese Journal of Pharmacology

    The Japanese Journal of Pharmacology 82(4), 281-286, 2000-04-01

    The Japanese Pharmacological Society

References:  50

Codes

  • NII Article ID (NAID)
    10008183720
  • NII NACSIS-CAT ID (NCID)
    AA00691188
  • Text Lang
    ENG
  • Article Type
    REV
  • ISSN
    00215198
  • NDL Article ID
    5362667
  • NDL Source Classification
    ZS51(科学技術--薬学)
  • NDL Call No.
    Z53-D199
  • Data Source
    CJP  NDL  J-STAGE 
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