Expression of Cyclooxygenase mRNA in the Livers of Mice With Interferon-γ Chronic Hepatitis

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Author(s)

Abstract

Interferon−γ(IFN−γ)transgenic mice expressed the IFN−γ gene in the liver and developed chronic hepatitis.The expression of cyclooxygenase(Cox)−1 and −2 mRNA were studied in the livers of these mice.A faint band of Cox−1 mRNA was observed in the livers of both normal and transgenic mice.Slight expression of Cox−2 mRNA was observed in the normal mouse liver, and this mRNA expression was induced in the transgenic mouse liver.The present results showed the induction of Cox−2 mRNA expression in the livers of transgenic mice with chronic hepatitis.

Journal

  • The Japanese Journal of Pharmacology

    The Japanese Journal of Pharmacology 83(4), 359-361, 2000-08-01

    The Japanese Pharmacological Society

References:  15

Codes

  • NII Article ID (NAID)
    10008184874
  • NII NACSIS-CAT ID (NCID)
    AA00691188
  • Text Lang
    ENG
  • Article Type
    SHO
  • ISSN
    00215198
  • NDL Article ID
    5501337
  • NDL Source Classification
    ZS51(科学技術--薬学)
  • NDL Call No.
    Z53-D199
  • Data Source
    CJP  NDL  J-STAGE 
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