書誌事項
- タイトル別名
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- Bioavailability of Calcium-bound Phosphoryl Oligosaccharides in Rats.
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The present study was undertaken to evaluate the Bioavailability of calcium-bound phosphoryl oligosaccharides (POs-Ca). POs-Ca was not hydrolyzed by artificial gastric acid. The gradual decrease of POs-Ca injected into the rat ligated jejunum loop was observed, suggesting that POs-Ca was hydrolyzed and absorbed in the small intestine. The overall rate of plasma glucose response after oral administration of POs-Ca to rats was similar to the case of administration of control saccharides, glucose and high-maltotetoraose syrup (TETRUP(R)-H). However, the glucose concentration of POs-Ca group at 0.25 h after administration was significantly lower than those of other groups. In the case of POs-Ca administration, plasma Ca concentration showed slight but significant increase during 0.25-0.5 h concurrent with the increase of plasma glucose . On the other hand, plasma P concentration decreased and then increased gradually from 2 h after the administration. Body weight gain, food intake and food efficiency of rats fed the diet containing 10% POs-Ca for 15 days were not different from those of rats fed control diet, and no diarrhea was observed in the POs-Ca group. The serum TG concentration of POs-Ca group was significantly lower than that of the control group. Other serum biochemical indices and organ (liver and cecum) weight were not significantly different among groups. From these results, it was assumed that the POs-Ca orally administered would be hydrolyzed into glucose, Ca, and P and then absorbed completely in the small intestine, therefore not causing acute diarrhea.
収録刊行物
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- Journal of Applied Glycoscience
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Journal of Applied Glycoscience 49 (2), 159-165, 2002
日本応用糖質科学会
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詳細情報 詳細情報について
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- CRID
- 1390001206293525376
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- NII論文ID
- 10008253606
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- NII書誌ID
- AN10453916
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- ISSN
- 13403494
- 18807291
- 13447882
- http://id.crossref.org/issn/13447882
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- COI
- 1:CAS:528:DC%2BD38Xkt1Cis7o%3D
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- NDL書誌ID
- 6142429
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- IRDB
- NDL
- Crossref
- CiNii Articles
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- 抄録ライセンスフラグ
- 使用不可