Four new bioactive bromophenols from the palauan Sponge Phyllospongia dendyi.

  • HATTORI TADAMASA
    Marine Biotechnology Institute, Shimizu Laboratories
  • KONNO AYA
    Marine Biotechnology Institute, Shimizu Laboratories National Cancer Center Research Institute
  • ADACHI KYOKO
    Marine Biotechnology Institute, Shimizu Laboratories
  • SHIZURI YOSHIKAZU
    Marine Biotechnology Institute, Shimizu Laboratories

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Abstract

Four new bromophenols and a known bromophenol derivative have been isolated from the Palauan sponge Phyllospongia dendyi. The structures of these new compounds were established using nuclear magnetic resonance and mass spectral data. They showed antimacroalgal activity with IC50 values of 0.02-0.05 p.p.m. Moreover, all compounds were antimicroalgal against various classes of algae at concentrations of 0.5-5.0 p.p.m.

Journal

  • Fisheries science

    Fisheries science 67 (5), 899-903, 2001

    The Japanese Society of Fisheries Science

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