子豚の群編成と末梢血コルチゾール濃度,リンパ球幼若化能,単球貪食能およびフィトヘマグルチニン(PHA)皮内反応

• 出口 栄三郎

  鹿児島大学農学部獣医学科家畜内科学講座

書誌事項

タイトル別名

• Effects of Grouping of Piglets on Plasma Cortisol Concentration, Lymphocyte Blastogenesis and Phagocytotic Function of Monocytes in Peripheral Blood and on Intradermal Response to Pytohemagglutinin.
• 子豚の群編成と末梢血コルチゾール濃度，リンパ球幼若化能，単球どん食能およびフィトヘマグルチニン（ＰＨＡ）皮内反応
• コブタ ノ グン ヘンセイ ト マッショウケツ コルチゾール ノウド リンパキ

抄録

This experiment was carried out to reexamine the effects of grouping of piglets on the concentration of plasma cortisol, total and differential leukocyte counts, the phagocytic functions of monocytes and the function of lymphocytes in vivo and in vitro. Twelve specific-pathogen-free piglets from 8 piglets/litter and 4 piglets/litter were used. At 63 days of age, 4 piglets of 8 piglets of a litter (Group A) were moved to the pen where 4 piglets of the other litter (Group B) were housed, and they were reared together for 13 days. The remaining 4 piglets of 8 piglets were not moved but reared for 13 days as control piglets. After grouping, all piglets of Group B attacked violently the piglets of Group A and bited their shoulders and ears for 2 hours. The concentrations of plasma cortisol at 2 hours after grouping were significantly higher as compared with those on 3rd day before grouping. After then, the plasma cortisol concentrations dropped to the normal and base-line levels at 24 hours after grouping. A significant difference in plasma cortisol concentration was not observed between Groups A and B. The numbers of total and differential leukocytes were almost same throughout the experiment. The proliferative responses of peripheral blood mononuclear cells induced with the mitogens such as phytohemagglutinin (PHA) and pokeweed mitogen in vitro were significantly decreased on 3rd day after grouping compared with those on 3rd day before grouping in Group B. The intradermal response to PHA in vivo and the Phagocytotic function of monocytes were significantly reduced in all piglets until 14 days after grouping. In control piglets, a slight increase of plasma cortisol was also found, and the suppression of intradermal response to PHA was observed for 13 days.<br>These data suggested that grouping puts piglets under stress and suppresses the functions of lymphocytes and monocytes at least for 13 days after grouping.

収録刊行物

• 日本養豚学会誌

  日本養豚学会誌 35 (1), 1-8, 1998

  日本養豚学会

キーワード

• Grouping
• immune suppression
• lymphocyte function
• phagocytotic function
• piglets

詳細情報

• CRID: 1390001204707977088
• NII論文ID: 10008284881
• NII論文ID: 10029862360
• NII書誌ID: AN10202971
• DOI: 10.5938/youton.35.1
• ISSN: 1881655X
• ISSN: 0913882X
• NDL書誌ID: 4425470
• Web Site: https://agriknowledge.affrc.go.jp/RN/2030571323
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4425470
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • IRDB
  • NDL
  • Crossref
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可