犬の慢性心不全に対するＴＤＫ‐３６（木防い湯）の臨床応用

• 小山 秀一

  日本獣医畜産大学獣医内科学教室

• 竹村 直行

  日本獣医畜産大学獣医内科学教室

• 本好 茂一

  日本獣医畜産大学獣医内科学教室

書誌事項

タイトル別名

• Clinical Application of TKD-36 (Moku-boi-to) on Chronic Heart Failure in Dogs.
• イヌ ノ マンセイ シンフゼン ニ タイスル TKD-36 モクボイトウ ノ

抄録

A multi-central clinical trial was conducted to assess the effect of TKD-36 (Moku-boi-to)on chronic heart failure in dogs. TKD-36 (75, 150 or 300 mg/kg/day, divided b. i. d., p. o.) or placebo were administered for 4 weeks to dogs showing signs of chronic heart failure. Overall assessment and various clinical evaluation of clinical symptoms in dogs treated with TKD-36 (150 and 300 mg/kg/day) were excellent compared to that in dogs treated with the placebo. But the dose of 75 mg/kg/day of TKD-36 did not improve any clinical signs of heart failure as same as the placebo group. No adverse reactions attributable to TKD-36 administration were observed, confirming its safety in this species. Based on efficacy, safety and overall assessment analyses, the optimal dosage of TKD-36 is from 150 to 300 mg/kg/day.<BR>These results clearly indicate that TKD-36 is an excellent drug for a treatment of the chronic heart failure in dogs.

収録刊行物

• 動物の循環器

  動物の循環器 29 (2), 59-78, 1996

  日本獣医循環器学会

キーワード

• chronic heart failure
• dog
• kampo medicine
• moku-boi-to
• TKD-36

詳細情報

• CRID: 1390001206457195392
• NII論文ID: 10008286971
• NII書誌ID: AN10192925
• DOI: 10.11276/jsvc1984.29.59
• ISSN: 18835260
• ISSN: 09106537
• NDL書誌ID: 4107691
• Web Site: https://ndlsearch.ndl.go.jp/books/R000000004-I4107691
• Web Site: https://search.jamas.or.jp/link/ui/1997074968
• 本文言語コード: ja
• データソース種別:
  • JaLC
  • NDL
  • CiNii Articles
• 抄録ライセンスフラグ: 使用不可