ロードアイランドレッド種鶏における自然発生性不整脈および壁内冠状動脈病変の出現時期  [in Japanese] Electrocardiographic and Cardiopathological Studies on the Time of Occurrence of Spontaneous Arrhythmias and Intramural Coronary Arteriosclerosis in Rohde Island Red Chickens  [in Japanese]

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Author(s)

    • 向井 真 MUKAI Shin
    • 東京農工大学農学部獣医学科家畜病理学教室 Department of Veterinary Pathology, Faculty of Agriculture, Tokyo University of Agriculture and Technology
    • 町田 登 MACHIDA Noboru
    • 東京農工大学農学部獣医学科家畜病理学教室 Department of Veterinary Pathology, Faculty of Agriculture, Tokyo University of Agriculture and Technology
    • 西村 昌晃 [他] NISHIMURA Masaaki
    • 東京農工大学農学部獣医学科家畜病理学教室 Department of Veterinary Pathology, Faculty of Agriculture, Tokyo University of Agriculture and Technology
    • 中村 孝 NAKAMURA Takashi
    • 東京農工大学農学部獣医学科家畜病理学教室 Department of Veterinary Pathology, Faculty of Agriculture, Tokyo University of Agriculture and Technology
    • 桐生 啓治 KIRYU Keiji
    • 東京農工大学農学部獣医学科家畜病理学教室 Department of Veterinary Pathology, Faculty of Agriculture, Tokyo University of Agriculture and Technology

Abstract

ロードアイランドレッド種鶏(RIR)における不整脈の好発生性と壁内冠状動脈の硬化性変化(内膜肥厚)との関連性を明らかにする目的で,RIR60羽および白色レグホン種(WL)60羽を用いて,不整脈と心室壁内冠状動脈における硬化性変化の発生時期に注目しつつ,孵化直後から12ヵ月間にわたって経時的な心電図検査および心室の病理学的検索を実施した。<BR>不整脈は7ヵ月齢~12ヵ月齢のRIR10羽に観察された(心房性期外収縮3羽,心室性期外収縮3羽および心室早期興奮症侯群4羽)。しかしながら,WLでの発生は認められなかった。また,壁内冠状動脈病変の発生率および程度はRIRにおいて月齢とともに増大する傾向を示した。重度内膜肥厚病変の累積発生率について両品種間で比較すると,RIRはWLよりも有意に高かった(p<0.001)。さらに,RIRにおいて不整脈例での重度内膜肥厚病変の発生率は,非不整脈例に比べて有意に高かった(p<0.01)。これらの検索結果から,RIRにおける不整脈の好発生性.には壁内冠状動脈の硬化性変化が密接に関わっていることが示唆された。

The purpose of this study was to investigate the relationship between the higher incidence of arrhythmias and arteriosclerotic changes of the intramural coronary artery (consisting essentially of intimal thickening) in Rhode Island Red chickens (RIR). Electrocardiographic examinations and cardiopathological examinations of the ventricle were conducted with 60 RIR and 60 White Leghorn chickens (WL) during 12 months after hatching, focusing on the time of occurrence of arrhythmias and intimal thickening of the intramural coronary artery. Arrhythmias were observed in 10 RIR aged 7 to 12 months (atrial premature contraction : 3, ventricular premature contraction : 3, ventricular preexcitation syndrome : 4), but not in WL. In addition, the incidence and degree of vascular lesions tended to increase with advancing age. RIR showed a significantly higher cumulative incidence of the severe vascular lesion than WL (p<0.001). The rate of occurrences of the severe lesion was significantly higher in RIR with arrhythmias than in RIR with normal sinus rhythm (p<0.01). Consequently, this study show that the high incidence of arrhythmias in RIR is closely related to the sclerotic changes of the intramural coronary artery.

Journal

  • Advances in Animal Cardiology

    Advances in Animal Cardiology 29(2), 91-98, 1996-12-01

    Japanese Society of Veterinary Cardiology

References:  27

Codes

  • NII Article ID (NAID)
    10008287026
  • NII NACSIS-CAT ID (NCID)
    AN10192925
  • Text Lang
    JPN
  • Article Type
    ART
  • ISSN
    09106537
  • NDL Article ID
    4107694
  • NDL Source Classification
    ZR22(科学技術--農林水産--畜産)
  • NDL Call No.
    Z18-1508
  • Data Source
    CJP  NDL  J-STAGE  JASI 
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