Correlation between Erythropoietin and Lactate in Humans during Altitude Exposure.
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- Sakata Susumu
- Department of Physiology II, College of Nursing, Nara Medical University
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The plasma concentrations of both immunoreactive erythropoietin (EPO) and lactate were determined in four healthy untrained subjects at sea level and on the 2nd or 3rd day at altitudes (1,300 and 3,500 m). The mean plasma EPO (18.8 ± 1.6 mU/ml at sea level) increased significantly on the 3rd day at 1,300 m (25.5 ± 2.0 mU/ml, p < 0.05) and showed an almost three-fold increase on the 2nd day at 3,500 m (53.5 ± 3.7 mU/ml, p < 0.001). Likewise, the mean plasma lactate at 3,500 m (3.98 ± 0.27 mmol/l) was 3.6 times as high as that at sea level (1.11 ± 0.05 mmol/l) (p < 0.001). The plasma EPO concentrations were found to correlate well with the lactate concentrations at sea level and altitudes (r = 0.86, p < 0.01). These results are consistent with the well-known EPO/lactate response to altitudes and suggest that the circulating EPO concentration as well as blood lactate concentration can be used as an index of anaerobic condition.<br>
収録刊行物
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- The Japanese Journal of Physiology
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The Japanese Journal of Physiology 50 (2), 285-288, 2000
一般社団法人 日本生理学会
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詳細情報 詳細情報について
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- CRID
- 1390001205040967680
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- NII論文ID
- 10008291229
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- NII書誌ID
- AA00691224
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- COI
- 1:CAS:528:DC%2BD3cXksVCqu7c%3D
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- ISSN
- 18811396
- 0021521X
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- NDL書誌ID
- 5413580
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- PubMed
- 10880888
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- 本文言語コード
- en
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- データソース種別
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- JaLC
- NDL
- Crossref
- PubMed
- CiNii Articles
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- 使用不可