Protein Kinase C Inhibitors Attenuate Protective Effect of High Glucose against Hypoxic Injury in H9c2 Cardiac Cells

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Author(s)

Abstract

In this study, we demonstrated that PKC inhibitors significantly attenuated the cardioprotective effect produced by high-glucose (22 mM) treatment for 48 h against hypoxic injury in H9c2 cardiac cells. PKC activators mimicked the cardioprotective effect of high glucose. These results suggest a possible role of PKC activation in high-glucose-induced protection.<br>

Journal

  • The Japanese Journal of Physiology

    The Japanese Journal of Physiology 50(6), 645-649, 2000-12-01

    THE PHYSIOLOGICAL SOCIETY OF JAPAN

References:  19

Cited by:  1

Codes

  • NII Article ID (NAID)
    10008292576
  • NII NACSIS-CAT ID (NCID)
    AA00691224
  • Text Lang
    ENG
  • Article Type
    Journal Article
  • ISSN
    0021521X
  • NDL Article ID
    5706408
  • NDL Source Classification
    ZS8(科学技術--医学--解剖学・生理学・生化学)
  • NDL Call No.
    Z53-D40
  • Data Source
    CJP  CJPref  NDL  J-STAGE 
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