Blood Flow Structure Related to Red Cell Flow: A Determinant of Blood Fluidity in Narrow Microvessels

DOI Web Site Web Site PubMed 被引用文献9件 参考文献101件

書誌事項

タイトル別名
  • Blood Flow Structure Related to Red Cell Flow: Determinant of Blood Fluidity in Narrow Microvessels

この論文をさがす

抄録

The review article deals with phenomena of the blood flow structure (structuring) in narrow microvessels--capillaries and the adjacent arterioles and venules. It is particularly focused on the flow behavior of red blood cells (RBCs), namely, on their specific arrangements of mutual interaction while forming definite patterns of self-organized microvascular flow. The principal features of the blood flow structure in microvessels, including capillaries, include axial RBC flow and parietal plasma layer, velocity profile in larger microvessels, plug (or bolus) flow in narrow capillaries, and deformation and specific behavior of the RBCs in the flow. The actual blood flow structuring in microvessels seems to be a most significant factor in the development of pathological conditions, including arterial hypertension, brain and cardiac infarctions, inflammation, and many others. The blood flow structuring might become a basic concept in determining the blood rheological properties and disorders in the narrow microvessels. No solid theoretical (biorheological) basis of the blood flow structuring in microvessel has been found, but in the future it might become a foundation for a better understanding of the mechanisms of these properties under normal and pathological conditions in the narrowest microvessels 5 to 25 &mgr;m large. It is also a topic for further biorheological research directed to find the background of actual physiopathological phenomena in the microcirculation.<br>

収録刊行物

被引用文献 (9)*注記

もっと見る

参考文献 (101)*注記

もっと見る

キーワード

詳細情報 詳細情報について

問題の指摘

ページトップへ