A case of primary sclerosing cholangitis presenting transient hypoperfusion and treated with bezafibrate beneficially

• KITA Ryuichi

  Department of Gastroenterology, Osaka Red Cross Hospital

• OSAKI Yukio

  Department of Gastroenterology, Osaka Red Cross Hospital

• HACHIYA Tsutomu

  Department of Gastroenterology, Osaka Red Cross Hospital

• KIMURA Toru

  Department of Gastroenterology, Osaka Red Cross Hospital

• KOMEKADO Hideyuki

  Department of Gastroenterology, Osaka Red Cross Hospital

• SAWABU Tateo

  Department of Gastroenterology, Osaka Red Cross Hospital

• HATANO Hiromi

  Department of Gastroenterology, Osaka Red Cross Hospital

• TSUJI Kentaro

  Department of Gastroenterology, Osaka Red Cross Hospital

• MARUO Takanori

  Department of Gastroenterology, Osaka Red Cross Hospital

• KOKURYU Hiroyuki

  Department of Gastroenterology, Osaka Red Cross Hospital

• TAKAMATSU Seigo

  Department of Gastroenterology, Osaka Red Cross Hospital

• FUKUYAMA Takayuki

  Department of Gastroenterology, Osaka Red Cross Hospital

• TOMONO Naomi

  Department of Gastroenterology, Osaka Red Cross Hospital

• KOMIBUCHI Tomoo

  Department of Gastroenterology, Osaka Red Cross Hospital

• SHIMIZU Tatsuo

  Department of Gastroenterology, Osaka Red Cross Hospital

Bibliographic Information

Other Title

• 一過性血流障害を呈し，ｂｅｚａｆｉｂｒａｔｅにより血清ＡＬＰ値の著明な改善をみた原発性硬化性胆管炎の１例

Abstract

症例は64歳,男性．硬化性胆管炎としてウルソデオキシコール酸(UDCA)内服にて経過観察されていたが，胆道系酵素の上昇をきたし，精査のため入院．腹部超音波検査(US)にて高エコー，造影CTにて動脈-門脈シャントを内包する低吸収域として描出される区域性の血流障害を呈した．MRCP・ERCPにて肝内・肝外胆管は数珠状変化・帯状狭窄を呈し原発性硬化性胆管炎(PSC)と診断した，また肝生検にて，血流障害区域に周辺とくらべ強い線維化を確認した．3カ月後のCTでは血流異常像は消失傾向を示した．UDCA600mg/day経口投与に加え，bezafibrate400mg/day経口投与追加したところ，ALP値は速やかに低下傾向を示した．

Journal

• Nippon Shokakibyo Gakkai Zasshi

  Nippon Shokakibyo Gakkai Zasshi 99 (2), 170-178, 2002

  The Japanese Society of Gastroenterology

Keywords

• 原発性硬化性胆管炎
• 血流障害
• bezafibrate

Details

• CRID: 1390001206396387712
• NII Article ID: 10008361613
• NII Book ID: AN00192124
• DOI: 10.11405/nisshoshi1964.99.170
• COI: 1:STN:280:DC%2BD387ktlehtQ%3D%3D
• ISSN: 13497693
• ISSN: 04466586
• PubMed: 11877955
• Web Site: https://search.jamas.or.jp/link/ui/2002204235
• Text Lang: ja
• Data Source:
  • JaLC
  • PubMed
  • CiNii Articles
• Abstract License Flag: Disallowed