乳腺adenomyoepitheliomaの1例  本邦報告30例の検討

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タイトル別名
  • Adenomyoepithelioma of the Mammary Duct. A Case Report.
  • A CASE REPORT
  • 本邦報告30例の検討

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A 45-year-old woman was seen at the hospital because of pain of the breast, when an irregular shaped hard mass 17mm in diameter was found in the A area of left breast. Mammography revealed a tumor shadow with an irregular margin associated with minute calcification. Ultrasonography visualized an irregular, segmental hypoechoic tumor with heterogeneous inner structure. Malignancy was strongly suspected clinically, however, a needle biopsy cytology gave Class IV. So the tumor was extirpated. Histologically, it was a solid tumor 1.5cm in diameter in which two parts existed concomitantly; a part surrounded by large type myoepithelium around epithelium of lactiferous ducts showing ductal vacancy formation, and another part in which only myoepithelium formed cystic foci. The ductal epithelium was epithelial membrane antigen positive, and the myoepithelium was α-smooth muscle actin positive. Adenomyoepithelioma (AME) of the mammary duct was diagnosed.<br>A total of 30 cases including this case were analyzed. These lesions were predominantly found in the lateral side of the breast in middle to elderly woman over 50 years old. They manifested clinical findings suggestive of carcinoma and hence it is important not to make overdiagnosis. Four patients experienced local recurrence, but did not have distant metastasis. We think that partial excision of the breast may be an appropriate operative produre.

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