血清CEA高値を示した乳腺悪性葉状腫瘍の1例  [in Japanese] A CASE REPORT OF THE MALIGNANT PHYLLODES TUMOR OF THE BREAST WITH ELEVATED SERUM CEA LEVEL  [in Japanese]

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Abstract

症例は56歳の女性. 1 カ月半の間に急速に増大した右乳房腫瘤を主訴に当科を受診した.右乳房に大きさ13×10cmの弾性硬,表面は平滑,可動性良好な腫瘤を認めた.また血清CEA 値( RIA 法) が 9.27ng/ml と高値であった. 乳腺葉状腫瘍を疑い, 腫瘍切除術を施行した.病理組織学的に悪性所見を認めたため,単純乳房切除術を追加施行した.血清 CEA 値は術後から漸減し, 術後1 カ月目には 5.98ng/ml となった. また腫瘍の免疫組織染色では,CEAおよびp53が陽性であった.比較的稀な疾患とされる乳腺悪性葉状腫瘍のうち,本症例のようにCEA陽性を示す乳腺悪性葉状腫瘍は再発をきたしやすいと報告されており,術後の厳重な経過観察を要する.

A 56-year-old woman was admitted to the hospital because of a large tumor in the right breast. The tumor was 13×10cm in size, with elastic firm consistency. With a suspicion of phyllodes tumor, an excision of the tumor was performed and it was confirmed histopathologically. Simple mastectomy was added because of a small malignant component in the tumor with H-E stain. The tumor was also positive for both CEA and p53 with immunohistochemical stain. Elevated serum CEA level of 9.27ng/ml before operation was reduced to 5.98ng/ml in one month after the removal of the tumor. Malignant phyllodes tumors of the breast are relatively rare. Of these tumors, that with positive CEA stain has been reported to be prone to recur. Strict postperative follow-up would be mandatory for the patient.

Journal

  • Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association)

    Nihon Rinsho Geka Gakkai Zasshi (Journal of Japan Surgical Association) 62(2), 368-372, 2001-02-25

    Japan Surgical Association

References:  14

Codes

  • NII Article ID (NAID)
    10008388014
  • NII NACSIS-CAT ID (NCID)
    AA11189709
  • Text Lang
    JPN
  • Article Type
    NOT
  • ISSN
    13452843
  • Data Source
    CJP  J-STAGE 
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